Dr. Christian Rolando

ChristianRolando
Professor
Laboratoire de Biophysique
Faculté des Sciences
Pharmaceutiques et Biologiques
Office: 33 (0)3 20 43 49 77
FAX: 33 (0)3 20 62 69 54
E-mail: Christian.Rolando@univ-lille1.fr

Research Interest

Dr. Rolando is a professor at the Université de Lille, in the Laboratory of Biophysical. He has developed with the French manufacturer of mass spectrometers Nermag (which has now ceased its activity) many new devices for manipulating ions in triple quadrupole collision cells. These devices are now incorporated in the so-called linear Q-traps. He is well recognized for his expertise in both organic synthesis and physical organic chemistry, particularly for the study of polyphenols reactivity. For example, with his colleagues, he has demonstrated that radical scavenging by electron transfer is more important for accounting on the antioxidant properties of flavonoids than hydrogen abstraction. Dr Rolando is well recognized as an expert in mass spectrometry moved towards proteomics, he is responsible of the Mass Spectrometry/Proteomics facility which is setup with state-of-the-arts proteomics for various projects in collaboration with biological teams in France and Europe. His research now is mainly focused in the development of microfluidics device for high throughput proteomics and new analytical devices by combining his expertise in organic synthesis and analytical chemistry. With his colleagues, he has developed for Biosynthec Company a new method for quantifying and identifying free radicals based on mass spectrometry, allowing optimizing a filter, which removes free radicals in cigarette smoke.

References

  • Mirabaud, Sigrid; Rolando, Christian; Regert, Martine. Molecular Criteria for Discriminating Adipose Fat and Milk from Different Species by NanoESI MS and MS/MS of Their Triacylglycerols: Application to Archaeological Remains. Analytical Chemistry (Washington, DC, United States) 2007, 79, 6182-6192.
  • Tokarski, Caroline; Martin, Elisabeth; Rolando, Christian; Cren-Olive, Cecile. Identification of Proteins in Renaissance Paintings by Proteomics. Analytical Chemistry 2006, 78, 1494-1502.
  • Tokarski, Caroline; Cren-Olive, Cecile; Fillet, Marianne; Rolando, Christian. High-sensitivity staining of proteins for one- and two-dimensional gel electrophoresis using post migration covalent staining with a ruthenium fluorophore. Electrophoresis 2006, 27, 1407-1416.